During the last years, my laboratory contributed to the understanding of the mechanisms underlying both pharmacological effects of cannabinoids and the physiological functions of the ECS. I will discuss our studies on the mechanisms of action of CB1 receptors in the brain, both from the pharmacological and physiological points of view.
The endogenous endocannabinoid system is the largest receptor system in the brain. 10 times larger than the endogenous morphine system. Could faults in this massive receptor network have negative effects on health? Dr Ross look at the hypothesis that endocannabinoid deficiency disorder is a possible cause of disease.
Variations between cannabis preparations and potencies have long vexed patients and practitioners alike. Consistent results depend on consistent absorption by the body. In this presentation, Dr Shade reviews common routes of administration, then takes us through his work on lipid nanoparticle delivery systems.
The effect of cannabis on the physiology of cellular processes is greatly affected by its components being herbal, not single purified substances. This lecture allows a more informed understanding of this complex herbal medicine for clinical use.